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Natural Product Research
Formerly Natural Product Letters
Volume 33, 2019 - Issue 21
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Research Articles

A new oleanane triterpene from the leaves of Ficus hirta

Dao Duc ThienNatural Products Research Laboratory, Institute of Chemistry, Vietnam Academy of Science and Technology, Cau Giay, Ha Noi, Vietnam; View further author information
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Tran Duc DaiDepartment of Chemistry, Graduate University of Science and Technology, Vietnam Academy of Science and Technology Cau Giay, Ha Noi, Vietnam; ;Department Medicine and Pharmacy, Tan Trao University, Yen Son District, Tuyen Quang, Vietnam; View further author information
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Nguyen Hoang SaDepartment of Chemistry, University of Khanh Hoa, Nha Trang, Khanh Hoa, Vietnam; View further author information
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NguyenThi LieuNatural Science Department, Hanoi Petropolitan University, Cau Giay, Ha Noi, Vietnam; View further author information
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Trinh Thi ThuyNatural Products Research Laboratory, Institute of Chemistry, Vietnam Academy of Science and Technology, Cau Giay, Ha Noi, Vietnam; ;Department of Chemistry, Graduate University of Science and Technology, Vietnam Academy of Science and Technology Cau Giay, Ha Noi, Vietnam; View further author information
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Nguyen Thi Hoang AnhNatural Products Research Laboratory, Institute of Chemistry, Vietnam Academy of Science and Technology, Cau Giay, Ha Noi, Vietnam; ;Department of Chemistry, Graduate University of Science and Technology, Vietnam Academy of Science and Technology Cau Giay, Ha Noi, Vietnam; View further author information
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Tran Duc QuanNatural Products Research Laboratory, Institute of Chemistry, Vietnam Academy of Science and Technology, Cau Giay, Ha Noi, Vietnam; View further author information
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Le Quoc ThangDepartment of Chemistry, Hue University’s College Education, Hue, Vietnam; View further author information
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Domenico V. DelfinoSection of Pharmacology, Department of Medicine, University of PerugiaPerugia, ItalyView further author information
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Nguyen Thanh TamNatural Products Research Laboratory, Institute of Chemistry, Vietnam Academy of Science and Technology, Cau Giay, Ha Noi, Vietnam; ;Department of Chemistry, Graduate University of Science and Technology, Vietnam Academy of Science and Technology Cau Giay, Ha Noi, Vietnam; Correspondence[email protected]
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Pages 3065-3069 | Received 03 Jul 2018, Accepted 24 Aug 2018, Published online: 06 Nov 2018
 
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Abstract

Repeated column chromatography of the n-hexane extract of Ficus hirta leaves (Moraceae) led to isolation of a new oleanane triterpene, 3β-hydroxy-11-oxo-olean-12-enyl-3-stearate (1) in addition to three known compounds, taraxerol (2), 3β-acetoxy-11α-methoxy-12-ursene (3) and 3β-acetoxy-11α-hydroxy-12-ursene (4). Their structures were elucidated by spectroscopic methods and by comparison with data reported in the literatures.

Graphical Abstract

Acknowledgments

The authors are grateful to Assoc. Prof. Do Huu Thu for identification of plant samples and MSc Dang Vu Luong for NMR.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by the Ministry of Science and Technology of Vietnam under Grant (grant number NĐT.33.ITA/17) and Italian Ministero degli Affari Esteri e della Cooperazione Internazionale (grant number MAECI).

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Related Research Data

A new oleanane triterpene from the leaves of Ficus hirta
Source: Figshare
A new oleanane triterpene from the leaves of Ficus hirta
Source: Figshare

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