Natural Product Research

Formerly Natural Product Letters

Volume 33, 2019 - Issue 21

386

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Research Articles

Centaurea microcarpa Coss. & Dur. (Asteraceae) extracts: New cyanogenic glucoside and other constituents

Samia BaatoucheUnité de recherche Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université des Frères Mentouri Constantine, Constantine, Algérie;

Thamere CherietUnité de recherche Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université des Frères Mentouri Constantine, Constantine, Algérie; ;Département de chimie, Faculté des sciences, Université Mohammed Boudiaf-M’sila, M’sila, Algérie;

Djamel SarriDépartement de Biologie, Faculté des sciences, Université Mohammed Boudiaf-M’Sila, M’Sila, Algérie;

http://orcid.org/0000-0003-3617-1162

Ratiba MekkiouUnité de recherche Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université des Frères Mentouri Constantine, Constantine, Algérie;

Ouahiba BoumazaUnité de recherche Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université des Frères Mentouri Constantine, Constantine, Algérie;

Samir BenayacheUnité de recherche Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université des Frères Mentouri Constantine, Constantine, Algérie;

Fadila BenayacheUnité de recherche Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université des Frères Mentouri Constantine, Constantine, Algérie;

Ignacio BrouardInstituto de Productos Naturales y Agrobiología-CSIC, Instituto Universitario de Bio-Orgánica ‘Antonio González’, Universidad de La Laguna, La Laguna, Tenerife, Spain

Francisco LeónInstituto de Productos Naturales y Agrobiología-CSIC, Instituto Universitario de Bio-Orgánica ‘Antonio González’, Universidad de La Laguna, La Laguna, Tenerife, Spain

Ramdane SeghiriUnité de recherche Valorisation des Ressources Naturelles, Molécules Bioactives et Analyses Physicochimiques et Biologiques (VARENBIOMOL), Université des Frères Mentouri Constantine, Constantine, Algérie; Correspondence[email protected]

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Abstract

The phytochemical investigation of both chloroform and ethyl acetate extracts of Centaurea microcarpa Coss. & Dur. led to the isolation of a new cyanogenic glucoside 6'-methacrylate prunasin (3) together with seven known compounds: hydroxy-11β,13-dihydro onopordaldehyde (1), β-sitosterol (2), daucosterol (4), nepetin (5), prunasin (6), astragalin (7) and 7-O-β-D-glucopyranosyl centaureidin (8). Their structures were established by spectral analysis, mainly UV, IR, ESI-MS, 1D & 2D-NMR experiments (COSY, HSQC, HMBC and ROESY).

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Centaurea microcarpa Coss. & Dur. (Asteraceae) extracts: New cyanogenic glucoside and other constituents

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Centaurea microcarpa Coss. & Dur. (Asteraceae) extracts: New cyanogenic glucoside and other constituents

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