Minor acetylated metabolites from Euphrasia rostkoviana.

Abstract

The phenylethanoids rostkovianoside, 6′-O-acetylcrassifolioside and the flavonoid rutin 3‴-acetate, were isolated from the methanolic extract of the aerial parts of Euphrasia rostkoviana Hayne. The structures of these previously undescribed compounds were elucidated by interpretation of spectroscopic data. The acetylation of rutin was also carried out and four ester derivatives were spectroscopically characterized. Finally, a chromatographic method was established to easily identify the acetylated position.

Graphical Abstract

Keywords:

• Euphrasia rostkoviana
• Orobanchaceae
• rutin
• rutin acetate
• rostkovianoside
• phenylethanoid glycosides
• iridoids

Acknowledgements

The authors are grateful to Dr. C. Vender, Dr. F. Scartezzini and Dr. N. Aiello of 'Consiglio per la ricerca in agricoltura e l’analisi dell’economia agraria', Centro di ricerca Foreste e Legno (Trento, Italy) for the collection and identification of plant. We acknowledge the excellent technical assistance of Mr. Sandro Gadotti.

Disclosure statement

The authors reported no potential conflict of interest.