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Natural Product Research
Formerly Natural Product Letters
Volume 34, 2020 - Issue 7
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Research Articles

Sesquiterpenes from the fruits of Illicium Simonsii maxim

Hang LiuDepartment of Pharmacy, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu Province, China; View further author information
,
Minghua ChenInstitute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; View further author information
,
Yongjun LangFengdu People's Hospital, Fengdu, Chongqing, China; View further author information
,
Xiaoxia WangNorth China University of Science and Technology, Tangshan, Hebei Province, ChinaCorrespondence[email protected]
View further author information
&
Pengyu ZhuangNorth China University of Science and Technology, Tangshan, Hebei Province, ChinaCorrespondence[email protected]
View further author information
Pages 903-908 | Received 07 Sep 2018, Accepted 16 Oct 2018, Published online: 11 Mar 2019
 
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Abstract

A new allo-cedrane sesquiterpene glycoside (1) and nine known compounds (2–10) were isolated from the ethanol extract of the fruit of Illicium simonii Maxim. Their structures were elucidated by spectroscopic methods, including 1D-, 2D-NMR, and HRESIMS. The absolute configuration of compound 1 was confirmed by CD experiments. Among them, compounds 1, 4, 5, and 7 displayed moderate anti-inflammatory activities by use of an in vitro bioassay.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This research program is supported by the National Natural Science Foundation of China (Nos. 21602102), Hebei Province Science Foundation for Youths (H2014209241), and CAMS Innovation Fund for Medical Sciences (CIFMS, 2016-I2M-2-002).

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