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Natural Product Research
Formerly Natural Product Letters
Volume 34, 2020 - Issue 7
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Research Articles

Toonapolyynes A–D, new polyynes from Toona ciliata

, , , , , & ORCID Icon show all
Pages 935-942 | Received 12 Sep 2018, Accepted 26 Oct 2018, Published online: 27 Dec 2018
 

Abstract

Phytochemical investigation on the leaves and twigs of Toona ciliata has led to the isolation of four new polyynes (14) and two knowns (5 and 6). Their structures were determined by extensive spectroscopic analysis (MS, UV, IR, and NMR) and Mosher’s method. All compounds were evaluated for their inhibitory activities against HepG2 human tumor cell line but were inactive.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work is supported by the National Natural Science Foundation of China (Nos. 81402813 and 81573302), the Guangdong Natural Science Funds for Distinguished Young Scholar (No. 2014A030306047), and the Science and Technology Planning Project of Guangdong Province, China (No. 2015A020211007).

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