Chemical constituents from the bark of bauhinia purpurea and their NO inhibitory activities

Abstract

Phytochemical studies led to the isolation of a new phenylpropanoid glucoside, named purpuroside (1), along with eight known compounds (2–9) from the bark of Bauhinia purpurea. The structure of the new compound was elucidated on the basis of its spectroscopic data. The absolute configuration of compound 2 was verified by X-ray diffraction analysis. Compounds 1, 2, 7, 8, and 9 inhibited NO production in mouse peritoneal macrophages with IC₅₀ values from 35.5 to 63.0 μM.

Keywords:

• Bauhinia purpurea
• phenylpropanoid glucoside
• norsesquiterpene
• X-ray
• NO inhibition

Disclosure statement

There is no conflict of interest among all authors.

Additional information

Funding

This work was supported by the Educational and Scientific Research Program for Young and Middle-age Instructor of Fujian province (NO. JAT160173), the National Natural Science Foundation of China (NO. 31700292).