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Natural Product Research
Formerly Natural Product Letters
Volume 34, 2020 - Issue 20
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Research Articles

One new xanthenone from the marine-derived fungus Aspergillus versicolor MF160003

Zhijun SongKey Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China; ;University of Chinese Academy of Sciences, Beijing, China; View further author information
,
Jieyu GaoKey Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China; ;School of Food and Biological Engineering, Hefei University of Technology, Hefei, China; View further author information
,
Jiansen HuKey Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China; ;University of Chinese Academy of Sciences, Beijing, China; View further author information
,
Hongtao HeKey Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China; ;University of Chinese Academy of Sciences, Beijing, China; View further author information
,
Pei HuangKey Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China; ;Department of Pediatrics, Affiliated Hospital of Zunyi Medical University, Zunyi, China; View further author information
,
Lixin ZhangState Key Laboratory of Bioreactor Engineering, East China University of Science of Technology, Shanghai, ChinaCorrespondence[email protected] [email protected]
View further author information
&
Fuhang SongKey Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, China; Correspondence[email protected] [email protected]
View further author information
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Pages 2907-2912 | Received 24 Jan 2019, Accepted 14 Mar 2019, Published online: 22 Apr 2019
 
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Abstract

A new xanthenone derivative, 3-hydroxy pinselin (1), together with five known analogues (2–6) were isolated from the marine-derived fungus Aspergillus versicolor MF160003. Their structures were identified by extensive 1D- and 2D-NMR, and high-resolution mass spectrometry data. Compounds 5 and 6 showed moderate bioactivities against BCG with MIC values of 40 and 20 μg/mL, respectively.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by grants from the National Key R&D Program of China (2018YFC0311002, 2017YFD0201203, 2017YFC1601300), the National Natural Science Foundation of China (31430002, 3132010391, 31600136), and the Fundamental Research Funds for the Central Public Welfare Research Institutes (Z0547).

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