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Natural Product Research
Formerly Natural Product Letters
Volume 34, 2020 - Issue 20
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Research Articles

Machaerinic acid 3-O-β-D-glucuronopyranoside from Calendula officinalis

Ahmed A. ZakiKey Laboratory of Preventive Veterinary Medicine and Biotechnology, Longyan University, Longyan, P.R. China; ;Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, EgyptCorrespondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-5462-6971
ORCID Icon &
Longxin QiuKey Laboratory of Preventive Veterinary Medicine and Biotechnology, Longyan University, Longyan, P.R. China;
Pages 2938-2944 | Received 17 Feb 2019, Accepted 20 Mar 2019, Published online: 10 Apr 2019
 
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Abstract

Machaerinic acid 3-O-β-D-glucuronopyranoside (1), along with ten known compounds (2-11) were isolated from the methanol extract of Calendula officinalis L. aerial parts. Their structures were confirmed by 1D and 2D NMR analysis and HRESIMS. Compound 1 was evaluated for the anti-proliferative activity against 95D and HT29 cancer cell lines and showed no cytotoxicity at the concentration of 100 µM.

Disclosure statement

No potential conflict of interest was reported by the authors.

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