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Abstract
Twenty-two diterpenoids (1–22), including two new ones (1, a tigliane-type diterpenoid and 8, an abietane-type diterpenoid) were isolated from the roots of Euphorbia fischeriana Steud. Among them, compounds 4, 7, 12, 14–16, 19–21 are isolated from this plant for the first time. Their structures were elucidated through extensive 1D, 2D NMR and the HRESIMS data. The 13C data of 4 is hereby presented for the first time. The macrocyclic diterpenes 1 and 2 showed marked enhancement of lysosomal biosynthesis after evaluation using lysoTracker staining method.
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Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This research was supported financially by grants from the National Science Foundation of China (21432010), Technological leading talent project of Yunnan (2015HA020), the Youth Innovation Promotion Association of CAS (2015323), and the Young Academic and Technical Leader Raising Foundation of Yunnan Province (to Y.Z.).
