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Abstract
Two new chromones, spororrminone A (1, (S)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid) and 2-epi-spororrminone A (2, (R)-5-hydroxy-2-methyl-4-oxo-2-((S)-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid), were isolated from an EtOAc extract of an endolichenic fungal strain Sporormiella irregularis (No. 71-11-4-1). The structures of these compounds were identified by spectroscopic analyses. The absolute configuration of 1 was established by single-crystal X-ray diffraction. Spororrminone A (1) and 2-epi-spororrminone A (2) represent the first examples of 2-(5-oxotetrahydrofuran-2-yl) chromones with 7-carboxylic group.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This work was financially supported by the National Natural Science Foundation of China [Nos. 3171101305 and 81673315]; the Chang Jiang Scholars Program from the Ministry of Education of China (No. Hao Gao, 2017); the Guangdong Natural Science Funds for Distinguished Young Scholar [No. 2017A03036027]; the Guangdong Special Support Program [No. 2016TX03R280]; the Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme [No. Hao Gao, 2014]; the Pearl River Nova Program of Guangzhou [No. 201610010021]; K. C. Wong Education Foundation [No. Hao Gao, 2016].
