https://orcid.org/0000-0003-2166-4992
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Abstract
The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesquiterpenes are reported for the first time in liverwort. P. viridissima was found to belong to the chemotype III (pinguisane/sacculatane) and shared chemical similarities with P. navicularis. Perrotettianal A was isolated and has shown strong cytotoxicity against ovarian cancer.
GRAPHICAL ABSTRACT
Acknowledgments
We are thankful to Nurunajah Ab Ghani and Pr. Yoshida for helpful technical assistance and mostly for spectroscopic analysis at the Faculty of Pharmaceutical Sciences (Tokushima Bunri). We are thankful to Cyril Antheaume for performing HPLC analysis.
Disclosure statement
No potential conflict of interest was reported by the authors.
