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Abstract
Cysestermerol A (1), a rare and new stilbene sestermer, was isolated from the whole herb of Cynodon dactylon. The planar and relative structures of 1 were elucidated based on HRESIMS, one- and two-dimensional NMR analyses, and its absolute configuration was further established by electronic circular dichroism calculations. Compound 1 obviously increased the glucose consumption in HepG2 cells equivalent to the positive control rosiglitazone and markedly inhibited the activity of α-glucosidase in vitro.
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Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
This work was financially supported by the Provincial Key Platforms and Major Scientific Research Projects of Guangdong Universities (No. 2017KTSCX101); the National Natural Science Foundation of China (No. 81773884); and Scientific Research Project of Guangdong Administration of Traditional Chinese Medicine (20181154).
