Phytochemical investigation of the flowers of Praxelis clematidea (Griseb.) R.M. King & H. Rob

Abstract

Chemical investigations of the flowers of Praxelis clematidea resulted in the isolation of 12 known compounds (1–12). Their structures were elucidated by extensive spectroscopic studies and chemical evidence. The structure and absolute configuration of 1 was precisely determined by a combination of 2 D NMR and quantum chemical calculations of ECD spectra analysis. Compounds 1, 4, 11 were isolated from the genus Praxelis for the first time, while 1–6, 8–12 were isolated from P. clematidea for the first time. The antibacterial activity of compounds 1, 2, 7, 9 were evaluated.

Graphical Abstract

Keywords:

• Praxelis clematidea
• Chemical constituents
• circular dichroism
• antibacterial activity

Disclosure statement

No potential conflict of interest was reported by the authors.

Correction Statement

This article has been republished with minor changes. These changes do not impact the academic content of the article.

Additional information

Funding

This work was supported by the the Key Project of Research and Development of Hainnan Province (ZDYF2018086, ZDYF2019151), the Program for Innovative Research Team in University (IRT-16R19) and the Hainan Province Natural Science Foundation of Innovative Research Team Project (2016CXTD007).