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Abstract
Two new aromadendrin rhamnosides, cissusfoliate A (1) and 3-epi-cissusfoliate A (2) together with seven known compounds (3-9) were isolated from the roots of Cissus rheifolia Planch. Their structures were determined by extensive spectroscopic methods. The absolute configurations of compounds 1-5 were assigned by combination of the J coupling constant values of H-2 and H-3 and the comparison of their experimental ECD spectra with those reported in literature. Compounds 1, 3 and 5-8 showed antioxidant effects on ORAC, ATBS and DPPH assays as well as antibacterial activity against six pathogenic bacterial strains. Their cytotoxicity against Hela, KB, MCF-7, HepG2 and HT-29 cell lines were also evaluated.
Graphical Abstract
Acknowledgements
We are grateful to the Applied Taxonomic Research Center and Dr. Anna Tria-Blasi from the Royal Botanic Garden, Kew for scientific name determination.
Disclosure statement
No potential conflict of interest was reported by the authors.
Funding
We are grateful for the financial support from the Thailand Research Fund (Grant no. RTA 5980002). C. Tantapakul is thankful for a scholarship under the Post-Doctoral Training Program from the Research Affairs and Graduate School, Khon Kaen University (Grant no. 58228). Partial support from the Center of Excellence for Innovation in Chemistry (PERCH-CIC), Ministry of Higher Education, Science, Research and Innovation is gratefully acknowledged.
Correction Statement
This article has been republished with minor changes. These changes do not impact the academic content of the article.
