Abstract
The red alga Chondria armata is known to produce and contain a rich diversity of secondary metabolites, such as domoic acid-related alkaloids and triterpene polyethers. Our investigation on red alga C. armata from Kagoshima coast, Japan, resulted in the isolation of two new triterpene polyethers, bandokorols A (1) and B (2). The structures of these compounds were determined based on spectroscopic data such as infrared (FTIR), 1H-NMR, APT, 1H–1H-COSY, HSQC, HMBC, NOESY and FAB mass spectrometry (HRFABMS). The anticancer potentials of these compounds were tested against adult T-cell leukaemia (ATL), S1T cells and their IC50 values are reported here.
Acknowledgements
We are grateful to Dr. Takeshi YASUMOTO (Japan Food Research Laboratories), Dr. Nobuhiro FUSETANI (Fisheries and Oceans Hakodate), Dr. Takenori KUSUMI (Tokyo Institute of Technology), Dr. Ryuta TERADA (Kagoshima University) and Dr. Osamu ARAKAWA (Nagasaki Univ.) for helpful comments and encouragement. We are thankful to the Research Center for the Pacific Islands at Kagoshima University for providing the opportunity to survey Yakushima Island.
Disclosure statement
The authors declare no conflicts of interest.