Publication Cover
Natural Product Research
Formerly Natural Product Letters
Volume 35, 2021 - Issue 24
230
Views
4
CrossRef citations to date
0
Altmetric
Research Articles

A new benzophenone with biological activities purified from Aspergillus fumigatus SWZ01

, , , , &
Pages 5710-5719 | Received 02 Jul 2020, Accepted 01 Sep 2020, Published online: 01 Oct 2020
 

Abstract

Strain SZW01 was isolated from sea sediment collected from Shenzhen in Guangdong province, China, and was later identified as Aspergillus fumigatus by16S rDNA sequence analysis. Various chromatographic processes led to the isolation and purification of three compounds from the fermentation culture of SZW01, including a new compound, 2,6'-dihydroxy-2,4'dimethoxy-8'-methyl-6-methoxy-acyl-ethyl-diphenylmethanone (1), and two known compounds: fumigaclavine C (2) and alternarosin A (3), as characterised by UV, IR, 1 D, 2 D-NMR and MS data. The antioxidant and α-glucosidase inhibitory activities of these compounds were evaluated. The result illustrated that compound 1 exhibited a moderate antioxidant activity and stronger α-glucosidase inhibitory activity than acarbose.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by Postdoctoral support plan of Harbin University of Commerce [grant No. 2017BSH003], University Nursing Program for Young Scholars with Creative Talents in Heilongjiang Province [grant No. UNPYSCT-2018140], Harbin University of Commerce “Young Innovative Talents” Support Program [grant No. 2019CX38], Harbin University of Commerce Doctoral Research Startup Fund [grant No. 2019DS111], Harbin University of Commerce “Young Innovative Talents” Support Program [grant No. 2019CX09].

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.