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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 5
247
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SHORT COMMUNICATION

Chemical constituents and anticholinesterase activity of the essential oil of Algerian Elaeoselinum thapsioides (Desf.) maire

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Pages 1359-1364 | Received 17 Oct 2020, Accepted 27 Dec 2020, Published online: 18 Jan 2021
 

Abstract

Elaeoselinum thapsioides (Desf.) Maire (Apiaceae) is an Algerian medicinal plant used in traditional medicine to treat different diseases. The essential oil obtained by hydrodistillation from the aerial parts of Elaeoselinum thapsioides growing wild in Algeria, was analyzed by GC-MS for the first time. Forty-five compounds were detected, accounting for 93.8% of the total oil, which was characterized by a high content of hydrocarbons derivatives of monoterpenes (75.9%). Myrcene (61.0%) was the principal constituent of the essential oil, followed by germacrene D (10.3%), α-pinene (6.5%) and β-pinene (2.9%). In vitro anticholinesterase activity of the essential oil was investigated by the Ellman method that evidenced a low acetylcholinesterase and butyrylcholinesterase inhibitory effect.

Acknowledgments

The authors are grateful to Dr Errol Vela (University of Montpelier 2, France) for the plant identification and to the financial support of the Ministère de l’EnseignementSupérieur et de la Recherche Scientifique (MESRES, Algeria).

Disclosure statement

No potential conflict of interest was reported by the authors.

Correction Statement

This article has been republished with minor changes. These changes do not impact the academic content of the article.

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