Hippotulosas A-D: four new sesterterpenes from marine sponge Hippospongia fistulosa Lendenfeld, 1889

Abstract

Four new sesterterpenes, named as hippotulosas A-D (1–4), and a known sesterterpene furospinulosin-1 (5) were isolated from the marine sponge Hippospongia fistulosa by various chromatographic methods. Their structures were established by extensive spectroscopic analyses (IR, HR-ESI-MS, 1D and 2D NMR) and by comparison of the spectral data with those reported in the literature.

Keywords:

• Marine sponge
• Hippospongia fistulosa
• Spongiidae
• hippotulosa
• sesterterpene

Acknowledgements

Authors would like to thank Prof. Do Cong Thung, the Institute of Marine Environment and Resources, VAST for the sample collection and taxonomic identification.

Disclosure statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Additional information

Funding

This research is funded by Vietnam Academy of Science and Technology under grant number TĐDLB0.01/20-22.