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Natural Product Research
Formerly Natural Product Letters
Volume 36, 2022 - Issue 20
159
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Short Communications

A new triarylindanone and a new isobenzofuranone derivative from Selaginella tamariscina

, , , , , , & show all
Pages 5387-5392 | Received 18 Mar 2021, Accepted 26 May 2021, Published online: 28 Jun 2021
 

Abstract

A new triarylindanone, namely selagindanone A (1), and a new isobenzofuranone (2), 3,4-bis(4-hydroxyphenyl)isobenzofuran-1(3H)-one, were isolated from Selaginella tamariscina. Their structures were elucidated by comprehensive spectroscopic and mass spectrometric analyses, including 1 D-, 2 D-NMR and HR-ESI-MS. Compound 1 possesses a unique structural feature of triaryl-substituted in the skeleton of 1-indanone. In addition, compound 2 showed weak cytotoxicity against human hepatocellular carcinoma SMMC-7721 and HepG2 cell lines.

Graphical Abstract

Acknowledgements

We would like to acknowledge the NMR measurements by the Modern Analysis and Testing Center of CSU.

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by China Postdoctoral Science Foundation (2020M673289), Outstanding youth project of Education Department of Hunan Province (19B363), Natural Science Foundation of Hunan province (2018JJ2268 and 2019JJ50949), Scientific research project of changsha science and technology bureau (kq1907131) and Undergraduate Innovation Experiment Project of Hunan Normal University.

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