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Natural Product Research
Formerly Natural Product Letters
Volume 37, 2023 - Issue 7
192
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Research Articles

Two pairs of epimers and three undescribed diterpenoids from Pseudocaryopteris paniculata

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Pages 1074-1081 | Received 15 Apr 2021, Accepted 19 Sep 2021, Published online: 07 Oct 2021
 

Abstract

A phytochemical investigation on the petroleum ether partition of the whole plant of Pseudocaryopteris paniculata, yield seven new compounds: one phytanes diterpenoid (2Z,6E,10E) 14-keto-2,6,10-trimethyl pentadeca-2,6,10-trien-1-carboxylic acid (1), five clerodane diterpenoids: paniculatins A-E (2, 3a/3b, 4a/4b), one abietane diterpenoid: ent-uncinatone (5), together with 12 known compounds. Their structures were elucidated on the basis of 1D and 2D Nuclear Magnetic Resonance (NMR_, Infrared Radiation (IR), and mass spectroscopic data. Compound 2, 5, and 11 showed weak selective cytotoxic activity of 11 human cancer cell lines.

Graphical Abstract

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

Financial support from the National Nature Science Foundation of China (No. 21672152) is gratefully acknowledged.

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