The basic chemical substances of three medicinal parts from Rhododendron molle G. Don

Abstract

Rhododendron Molle G. Don belongs to Ericaceae family. As a toxic traditional Chinese medicine, its roots, flowers, and fruit are often mixed and substituted arbitrarily to treat rheumatoid arthritis in clinic. To clarify the main chemical basis of each medicinal part, and provide sufficient scientific basis for clinical application, analysis using HPLC-ELSD of the roots, flowers, and fruit from R. molle was established, and characteristic chemical constituents of them were separated by tracking. The structures were determined by NMR methods. Finally, 16, 21, and 18 compounds were obtained from the roots, flowers, and fruit, respectively. Overall, 49 compounds were obtained, of which 25 were identified for the first time in R. molle. Meanwhile, among the obtained compounds, 12, 11, and 6 characteristic peaks were identified from the roots, flowers, and fruit, respectively. Thus, the basic chemical substances of the medicinal parts of R. molle were determined initially.

Graphical Abstract

Keywords:

• Rhododendron Molle
• medicinal parts
• traceability separation
• characteristic peaks
• basic chemical substances

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by Xinglin Young Talent Program of Shanghai University of Traditional Chinese Medicine.