Lepiginosides A-D: three new triterpenoid saponins and a new farnesyl glycoside from the stembarks of Lepisanthes rubiginosa (roxb.) leenh

Abstract

Phytochemical investigation of methanolic extract of L. rubiginosa using modern chromatographic techniques has led to the isolation of three new triterpenoid saponins, lepiginosides A-C (1-3), a new farnesyl glycoside, lepiginoside D (4), together with lepisantheside B (5) and gleditsoside C (6). The characterization and structural elucidation of the isolated compounds were established by extensive spectroscopic data analysis and comparison with literature data. Moreover, the antibacterial activity against seven bacteria, but none is active.

Graphical Abstract

Keywords:

• Sapindaceae
• Lepisanthes rubiginosa
• triterpenoid saponins
• farnesyl glycoside
• lepiginoside
• antibacterial

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was financially supported by the Ministry of Education, Malaysia under FRGS-RACER Grant (600-IRMI/FRGS-RACER 5/3 (036/2019)).