https://orcid.org/0000-0002-5366-8464
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Abstract
Three new compounds, arneatas A-C (1–3), together with three known compounds (4–6) were isolated from the roots of Arnebia guttata Bunge. The structures were established on the basis of extensive spectroscopic data including NMR and HRESIMS. All the new compounds (1–3) were tested for their cytotoxic activity against two glioma cell lines (U118-MG and U373-MG) in vitro after treatment for 48 h. Compound 1 exhibited moderate cytotoxic activity against U118-MG and U373-MG glioma cell lines, with IC50 values of 10.4 and 17.5 µM, respectively.
Graphical Abstract
Disclosure statement
No potential conflict of interest was reported by the authors.
Additional information
Funding
The key project at central government level: the ability establishment of sustainable use for valuable Chinese medicine resources No: 2060302 Graduate student scientific research innovation projects in Baotou Medical College No: bycx2021010 Inner Mongolia Autonomous Region Chinese Medicine (Mongolian Medicine) Young and Middle aged Leading Talents Cultivation Project NO: 2022-[RC001] This work was supported by the key project at central government level: The ability establishment of sustainable use for valuable Chinese medicine resources under Grant [No: 2060302]; Graduate student scientific research innovation projects in Baotou Medical College [No: bycx2021010]; Inner Mongolia Autonomous Region Chinese Medicine (Mongolian Medicine) Young and Middle aged Leading Talents Cultivation Project NO: 2022-[RC001]