Abstract
One new cyclohexenone derivative, asperfumtone A (1) along with six known compounds were obtained from the coculture of Aspergillus fumigatus and Alternaria alternata associated with Coffea arabica. The configuration of 2 was first reported in the research. The structures were determined by extensive spectroscopic analyses, and ECD calculation. Compounds 3, 4 and 7 showed significant antifungal activities against coffee phytopathogens A. alternata and Fusarium incarnatum with MICs of 1 μg/mL. Compounds 1 and 2 showed weak antifungal activities against A. alternata and F. incarnatum with MICs of 32–64 μg/mL.
Acknowledgements
Thanks to the teachers in Analysis and Measurement Center of Yunnan University for their supports in NMR and MS spectra, and the teachers of Kunming Institute of Botany, Chinese Academy of Sciences for the ECD and optical rotation data.
Disclosure statement
The authors declare that they have no conflict of interest.