![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
Antibiotics have become increasingly ineffective in the face of bacterial resistance, particularly in hospitals. Interestingly, there is high demand for bioprospecting of secondary metabolites, particularly for treating multidrug-resistant clinical diseases. In fact, Rosemary has been used for its antiseptic properties dating back to antiquity. The aim of this research is to evaluate the effectiveness of Rosmarinus officinalis essential oil against multidrug-resistant clinical bacterial pathogens. Results showed promising antibacterial activity against seven bacteria: Escherichia coli, Enterobacter cloacae, Staphylococcus aureus, Serratia odorifera, Klebsiella pneumoniae, Klebsiella oxytoca, Aeromonas hydrophila with MIC values of 35.7, 17.85, 71.4, 8.9, 17.8, 285.7, 35.7 µg/ml respectively and MBC values of 142.8, 71.4, 285.7, 35.7, 71.4, 571.5,71.4 µg/ml respectively. This study suggests that Rosmarinus essential oil can be used as a therapeutic agent in the fight against a wide range of multi-resistant bacteria.
Graphical Abstract
Acknowledgements
We would like to express our gratitude to the entire personnel of the Akid Lotfi central laboratory at the Laghouat hospital for their invaluable assistance in collecting reagents and operating various types of equipment.
Disclosure statement
We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome.