Efferent unmasking of speech-in-noise encoding?

Abstract

Objective

The medial olivocochlear (MOC) reflex provides efferent feedback from the brainstem to cochlear outer hair cells. Physiologic studies have demonstrated that the MOC reflex is involved in “unmasking” of signals-in-noise at the level of the auditory nerve; however, its functional importance in human hearing remains unclear.

Design

This study examined relationships between pre-neural measurements of MOC reflex strength (click-evoked otoacoustic emission inhibition; CEOAE) and neural measurements of speech-in-noise encoding (speech frequency following response; sFFR) in four conditions (Quiet, Contralateral Noise, Ipsilateral Noise, and Ipsilateral + Contralateral Noise). Three measures of CEOAE inhibition (amplitude reduction, effective attenuation, and input-output slope inhibition) were used to quantify pre-neural MOC reflex strength. Correlations between pre-neural MOC reflex strength and sFFR “unmasking” (i.e. response recovery from masking effects with activation of the MOC reflex in time and frequency domains) were assessed.

Study sample

18 young adults with normal hearing.

Results

sFFR unmasking effects were insignificant, and there were no correlations between pre-neural MOC reflex strength and sFFR unmasking in the time or frequency domain.

Conclusion

Our results do not support the hypothesis that the MOC reflex is involved in speech-in-noise neural encoding, at least for features that are represented in the sFFR at the SNR tested.

Keywords:

• Efferent
• medial olivocochlear reflex
• frequency following response
• otoacoustic emissions

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This research was funded by the National Institutes of Health, National Institute on Deafness and other Communication Disorders [F30 DC01418 & K01DC017192].