Combined Tinidazole and Doxycycline Prophylaxis in Colorectal Surgery: An Interhospital Trial

Abstract

There were no significant differences between randomized groups on either preoperative tinidazole or placebo added to pre-, per-, and postoperative doxycycline. Cases of anaerobic infection among the placebo patients as well as a general trend of the parameters studied suggest that tinidazole gives added protection, i.e. that antibiotic prophylaxis should also comprise anaerobic microbes.

Key-words:

• Antibiotic prophylaxis
• colon
• colon
• malignant tumor of
• colon surgery