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Scandinavian Journal of Gastroenterology Volume 15, 1980 - Issue sup59
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Research Article

Combined Tinidazole and Doxycycline Short Term Chemotherapeutic Prophylaxis in Gastro-intestinal Surgery

K.-E. Gierckskya Department of Surgery & Microbiology University of Tromsø, Tromsø, Norway;b Department of Surgery, Rikshospitalet, The National Hospital, University of Oslo, Oslo, Norway
,
E. Christiansena Department of Surgery & Microbiology University of Tromsø, Tromsø, Norway
,
L. Bergea Department of Surgery & Microbiology University of Tromsø, Tromsø, Norway
,
J. Fuglesanga Department of Surgery & Microbiology University of Tromsø, Tromsø, Norway
&
J. A. Johnsona Department of Surgery & Microbiology University of Tromsø, Tromsø, Norway
Pages 41-44 | Published online: 03 Jul 2023
 
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Abstract

Infectious complications following gastro-intestinal surgery can be reduced with properly administered antimicrobial agents. One single preoperative dose of doxycyline (200mg) and tinidazole (2g) gave a highly significant reduction of infectious complications in a controlled clinical study of 307 patients undergoing elective gastrointestinal surgery.

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