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Some miRNA expressions and their targets in ischemic stroke

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Pages 1224-1262 | Received 07 Feb 2021, Accepted 02 Jul 2022, Published online: 23 Jul 2022
 

Abstract

Ischemic stroke (IS) is a global health challenge leading to life-long disabilities or the deaths of patients. IS is a complex disease where genetic and environmental factors are both concerned with the pathophysiology of the condition. Here, we aimed to investigate various microRNA (miRNA) expressions and their targets in IS. A rapid and accurate diagnosis of acute IS is important to perform appropriate treatment. Therefore, there is a need for a more rapid and simple tool to carry out an acute diagnosis of IS. miRNAs are small RNA molecules serving as precious biomarkers due to their easy detection and stability in blood samples. The present systematic review aimed to summarize previous studies investigating several miRNA expressions and their targets in IS.

Acknowledgment

The authors thank Numan Duran for language editing.

Authors’ contributions

Ummugulsum Can and Ebru Marzioglu were involved in the design and writing the review.

Disclosure statement

The authors have no conflict of interests to declare concerning the review. The authors have read the manuscript and have agreed to submit it in its current form for consideration to be published in the journal.

Funding

The author(s) reported there is no funding associated with the work featured in this article.

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