Synthesis of 9-Fluorenemethyl Boranophosphonodiphosphate Via an H-Phosphonate Approach

Hongyan Liu Department of Chemistry, Duke University, Durham, North Carolina, USA

Syed N. Hashmi Department of Chemistry, Duke University, Durham, North Carolina, USA

Barbara Ramsay Shaw Department of Chemistry, Duke University, Durham, North Carolina, USA

Abstract

9-Fluorenemethyl boranophosphonate 6 and its boranophosphonodiphosphate 7 were synthesized via an H-phosphonate approach. The method is efficient for the synthesis of acyclic compounds 6 & 7 , and can be explored for the synthesis of nucleoside 5′-deoxy boranophosphonodiphosphate.

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Synthesis of 9-Fluorenemethyl Boranophosphonodiphosphate Via an H-Phosphonate Approach

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Synthesis of 9-Fluorenemethyl Boranophosphonodiphosphate Via an H-Phosphonate Approach

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