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Original Articles

At Tachment of Cholesterol to Amino-LNA: Synthesis and Hybridization Properties

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Pages 1645-1647 | Published online: 05 Dec 2007
 

Abstract

Here, we present our synthesis of amino-LNA with a C6-linker and hybridization studies of these. A cholesterol moiety was attached at the end of the C6-linker. This resulted in drastic drops against DNA of the modified oligonucleotide.

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