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Original Articles

Simplified Analogues of Acyclonucleosides. Synthesis of 6-[N-Alkyl-N-(4-hydroxybutyl)amino]pyrimidine Derivatives

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Pages 1769-1777 | Received 08 Nov 1993, Accepted 15 Feb 1994, Published online: 24 Sep 2006
 

Abstract

The synthesis of some 6-alkylaminopyrimidine derivatives bearing a 4-hydroxybutyl chain as sugar mimic is described. These new compounds can be regarded as simplified, ring-opened analogues of purine acylonucleosides.

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