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Original Articles

An Alternative Route for Preparation of α-Methylphosphonyl-β, γ-Diphosphates of Thymidine Derivatives

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Pages 1031-1037 | Received 20 Jul 1993, Accepted 28 Dec 1993, Published online: 24 Sep 2006
 

Abstract

An alternative “one pot” synthesis of α-methylphosphonyl-β, γ-diphosphates of thymidine and 3′-azidothymidine is proposed. p-Toluene-sulphonic acid was used as desililating agent for triphosphate analogues.

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