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Nucleosides and Nucleotides Volume 13, 1994 - Issue 6-7
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Original Articles

The Synthesis of 4′-t-Butylcarbamyl- and 4′-p-Toluenesulphonamidyl-2′,3′-Dideoxy Pyrimidine Nucleoside Analogues

Lea Pickering School of Chemistry, The University of Birmingham, Edgbaston, Birmingham, U.K., B15 2TT
,
Baljinder S. Malhi School of Chemistry, The University of Birmingham, Edgbaston, Birmingham, U.K., B15 2TT; The Wellcome Foundation Ltd., South Eden Park Rd, Beckenham, Kent, UK
,
Paul L. Coe School of Chemistry, The University of Birmingham, Edgbaston, Birmingham, U.K., B15 2TT
&
Richard T. Walker School of Chemistry, The University of Birmingham, Edgbaston, Birmingham, U.K., B15 2TT
Pages 1493-1506 | Received 23 Nov 1993, Accepted 12 Jan 1994, Published online: 24 Sep 2006
 
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Abstract

The preparation of 4′-t-butylcarbamyl-2′,3′-dideoxy thymidine, uridine and 5-ethyl uridine nucleoside analogues and 4′-p-toluenesulphonamidyl-2′,3′-dideoxy thymidine and 5-ethyl uridine nucleoside analogues from L-pyroglutamic acid is reported.

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Related Research Data

Nucleoside Analogues: Synthesis and Bioactivity of Azanucleosides
Source: Wiley
Approach to Fully Substituted Cyclic Nitrones from N-Hydroxylactam Derivatives: Development and Application to the Total Synthesis of Cylindricine C
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