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Original Articles

Large Scale Synthesis of the Cap Part in Messenger RNA Using a New Type of Bifunctional Phosphorylating Reagent

, , , , &
Pages 1557-1567 | Received 24 Dec 1993, Accepted 19 Jan 1994, Published online: 24 Sep 2006
 

Abstract

Bifunctional phosphorylating reagents 1 and 2 were employed for the synthesis of the cap part, m7G7 pppG, from guanosine 5′-phosphates on a large scale without any protecting groups.

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