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Original Articles

Impairment of Streptomyces and Micromonospora Differentiation by Dna-Methylase Inhibitors

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Pages 1659-1670 | Received 01 Jan 1995, Accepted 08 Jun 1995, Published online: 24 Sep 2006
 

Abstract

The effect of several inhibitors of DNA methyltransferases has been tested on Streptomyces and Micromonospora cultures. Some of them (5-aza-2′-deoxycytidine, 5-azacytidine and L-ethionine), inhibited sporulation at concentrations that did not significantly affect growth.

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