OLigonucleotide (Cyanomethyl) Phosphonates

Reza Fathi Pharma Genics, Inc., 4 Pearl Court, Allendale, New Jersey, 07401

William Delaney Pharma Genics, Inc., 4 Pearl Court, Allendale, New Jersey, 07401

Qing Huang Pharma Genics, Inc., 4 Pearl Court, Allendale, New Jersey, 07401

Alan F. Cook Pharma Genics, Inc., 4 Pearl Court, Allendale, New Jersey, 07401

Abstract

A dinucleoside (cyanomethyl) phosphonate has been prepared, and its properties have been studied. This compound was converted into an oligonucleotide possessing alternating (cyanomethyl) phosphonate and phosphodiester backbone groups and its hybridization to complementary DNA and RNA sequences was studied versus methylphosphonate and phosphodiester controls.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

OLigonucleotide (Cyanomethyl) Phosphonates

Information for

Open access

Opportunities

Help and information

OLigonucleotide (Cyanomethyl) Phosphonates

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature