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I. NUCLEOSIDES: Chemistry

Novel Analogues of Tiazofurin by Lawesson Reagent Effected Cyclization

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Pages 313-316 | Published online: 16 Feb 2007
 

Abstract

2-Benzylthiazole-4-carboxamide 4 and 5-(β-D-ribofuranosylamino) thiazole-4-carboxamide 10 were synthesized from phenylacetylamino- and formylamino cyanoacetic acid esters 1a and 1b, respectively. The ribosylation reaction leading to 10 gave rise also to its α anomer as a minor product.

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