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Nucleosides and Nucleotides Volume 14, 1995 - Issue 3-5
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I. NUCLEOSIDES: Biophysics/Biochemistry

Substrate/Inhibitor Properties of Tumour Purine Nucleoside Phosphorylase

A. Bzowska Department of Biophysics, Institute of Experimental Physics, University of Warsaw, 93 Zwirki i Wigury, 00-089, Warsaw, Poland
,
L. Pogosjan Institute of Experimental Biology, Armenian Academy of Sciences, Erevan, 375044, Armenia
,
A. V. Ananiev Institute of Experimental Biology, Armenian Academy of Sciences, Erevan, 375044, Armenia
,
E. Kulikowska Department of Biophysics, Institute of Experimental Physics, University of Warsaw, 93 Zwirki i Wigury, 00-089, Warsaw, Poland
&
D. Shugar Department of Biophysics, Institute of Experimental Physics, University of Warsaw, 93 Zwirki i Wigury, 00-089, Warsaw, Poland; Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 36 Rakowiecka, 02-532, Warsaw, Poland
Pages 517-520 | Published online: 16 Feb 2007
 
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Abstract

Substrate/inhibitor properties of purine nucleoside phosphorylase (PNP), isolated from human lung and kidney tumour tissues, have been characterised and compared with those of the enzyme from the corresponding normal organs.

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