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Nucleosides and Nucleotides Volume 14, 1995 - Issue 3-5
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I. NUCLEOSIDES: Biological Activity

Synthesis and Antiviral Activity of 2 and 3-Substituted Imidazo[1,2-a]pyrimidine

A. Gueiffier Laboratoire de Chimie Organique Pharmaceutique, URA-CNRS 1111, Facultéa de Pharmacie, 15 Avenue Charles Flahault, 34060, Montpellier, France
,
Y. Blache Laboratoire de Chimie Organique Pharmaceutique, URA-CNRS 1111, Facultéa de Pharmacie, 15 Avenue Charles Flahault, 34060, Montpellier, France
,
J. P. Chapat Laboratoire de Chimie Organique Pharmaceutique, URA-CNRS 1111, Facultéa de Pharmacie, 15 Avenue Charles Flahault, 34060, Montpellier, France
,
A. Elhakmaoui Laboratoire de Chimie Organique, Universitéa Mohammed V, Facultéa des Sciences, Rabat, Maroc
,
E. M. Essassi Laboratoire de Chimie Organique, Universitéa Mohammed V, Facultéa des Sciences, Rabat, Maroc
,
G. Andrei Katholieke Universiteit Leuven, Rega Institute for Medical Research, Minderbroedersstraat, 10, B-3000, Leuven, Belgique
,
R. Snoeck Katholieke Universiteit Leuven, Rega Institute for Medical Research, Minderbroedersstraat, 10, B-3000, Leuven, Belgique
,
E. De Clercq Katholieke Universiteit Leuven, Rega Institute for Medical Research, Minderbroedersstraat, 10, B-3000, Leuven, Belgique
,
O. Chavignon Déapartement de Chimie Structurale, Facultéa de Pharmacie, Université d'Auvergne, 63001, Clermont-Ferrand, France
,
J. C. Teulade Déapartement de Chimie Structurale, Facultéa de Pharmacie, Université d'Auvergne, 63001, Clermont-Ferrand, France
&
F. Fauvelle Centre de Recherches du Service de Santéa des Arméaes, Unitéa de Biophysique, B. P. 87, 38702, La, Tronche Cedex, France
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Pages 551-554 | Published online: 16 Feb 2007
 
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Abstract

Synthesis of acyclo-C-nucleoside derivatives in the imidazo[1,2-a]pyrimidine series was reported. None of the evaluated compounds showed appreciable antiviral activity.

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