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Nucleosides and Nucleotides Volume 14, 1995 - Issue 3-5
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III. OLIGONUCLEOTIDES: Biophysics/Biochemistry

Diamino-Antraquinone: A New Intercalating Agent. Synthesis and Linking to Oligodeoxynucleotide

Lászió Puskás Institute of Plant Biology, Biological Research Centre Hungarian Academy of Sciences, P. O. Box 521, H-6701, Szeged, Hungary
,
József Czombos Department of Organic Chemistry, Attila József University, Szeged, Hungary
&
Sándor Bottka Institute of Plant Biology, Biological Research Centre Hungarian Academy of Sciences, P. O. Box 521, H-6701, Szeged, Hungary
Pages 967-968 | Published online: 16 Feb 2007
 
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Abstract

Phosphoramidite derivative of 1,4-diamino antraquinone was synthesized, characterized, and incorporated into oligonucleotides. Intercalative interaction between the dye and the nucleic acid was confirmed by CD spectroscopy.

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