Synthesis and Expression of Some Genes for Human Cytokines

Kiara R. Birikh Shemyakin-Ovchinnikov Institute of Bio-organic Chemistry, Russian Academy of Sciences, Moscow, 117871, Russia

Ekaterina N. Lebedenko Shemyakin-Ovchinnikov Institute of Bio-organic Chemistry, Russian Academy of Sciences, Moscow, 117871, Russia

Yuri A. Berlin Shemyakin-Ovchinnikov Institute of Bio-organic Chemistry, Russian Academy of Sciences, Moscow, 117871, Russia

Abstract

Intronless genes for human mature interleukin 1a (IL1a) and its receptor antagonist (IL1ra) have been synthesized and efficiently expressed in a specially devised bacterial plasmid vector as part of a versatile two-cistron prokaryotic expression system.

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Synthesis and Expression of Some Genes for Human Cytokines

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Synthesis and Expression of Some Genes for Human Cytokines

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