Deaths from colon cancer among farmers in Taiwan: a mortality odds ratio study

ABSTRACT

Few studies have examined the association between increased risk of colon cancer development and occupation of farming. Data thus far have been inconsistent with respect to a correlation between farming and colon cancer occurrence. This type of study has not been undertaken in Asia. The aim of this investigation was to utilize the mortality odds ratio (MOR) design to estimate the relative risk (RR) of mortality attributed to colon cancer in farmers in Taiwan. Utilizing Taiwan’s Death Certificate Registry, data were collected on subjects who died between 1997–2009. Our study group was comprised of individuals 50 years of age and higher who died of colon cancer, while the control group consisted of subjects the same age who died of all other causes excluding cancers. Multiple logistic regression was performed to compute the MOR adjusted for gender, age at death, year of death, marital status, and urbanization levels. Of the 32,456 farmers who died, 558 were attributed to die of colon cancer. Farmers in Taiwan had a significantly lower risk of mortality from colon cancer than non-farmers (MOR = 0.85, 95% CI = 0.78–0.93), similar to estimates reported in previous meta-analyses. Occupational physical activity or higher consumption of vegetables and fruits might have contributed to the lower risk of death due to colon cancer. The basis for these observations requires further examination as it appears that lifestyle is a crucial factor in colon cancer development.

KEYWORDS:

• Farmers
• colon cancer
• mortality odds ratio

Acknowledgments

This study was partly supported by a grant from the Ministry of Science and Technology, Executive Yuan, Taiwan (MOST-104-2314-B-037-015-MY3).