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Original Articles

Mouse mammary tumor virus as a model for viral carcinogenesis

Pages 545-550 | Received 04 Jun 1975, Accepted 27 Jun 1975, Published online: 19 Oct 2009
 

Evidence is presented suggesting that genetic control may be the limiting factor in mammary tumor virus (MTV) positive mammary oncogenesis. Studies with hybrid mice involving high and low MTV‐expressing murine strains suggest that expression of MTV in milk may not be as important in tumorigenesis as previously thought. The usefulness of the murine MTV model in the study of mammary malignancy is discussed.

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