Toxic effects of acrylamide in Japanese quail (coturnix coturnix ja pon ica)

Abstract

Japanese quail (n =32), dosed orally with acrylamide monomer, showed an LD50 (95% confidence interval) of 214 mg/kg (194–236) at d 1 after dosing and of 186 mg/kg (171–202) at d 4 and 7 after dosing. Effects on righting and on posture and gait were prominent neurological signs. Wing strength and tone were less affected. Recovery was suggested in both neurological signs and body weights.