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Journal of Toxicology and Environmental Health Volume 10, 1982 - Issue 4-5
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Original Articles

Studies of organotin‐schiff base complexes as new potential amebicidal agents

A. K. Saxena Department of Chemistry, University of Rajasthan, Jaipur, 302004, India
,
J. K. Koacher Department of Chemistry, University of Rajasthan, Jaipur, 302004, India
,
J. P. Tandon Department of Chemistry, University of Rajasthan, Jaipur, 302004, India
&
S. R. Das Microbiology Division, Central Drug Research Institute, Lucknow, 226001, India
Pages 709-715 | Received 15 May 1981, Accepted 05 May 1982, Published online: 19 Oct 2009
 
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Abstract

Some new organotin(IV) complexes of Schiff bases containing sulfur and fluorine were tested for their activity on axenically grown Entamoeba histolytica trophozoites (strain NIH‐20). Some of the complexes were found to be potentially active at low doses, and one compound, tri‐n‐butyltin (2‐fluorobcnzaldehyde‐S‐benzyldithiocarba‐zate), showed remarkable activity at an extremely low dose even after 48 h.

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Related Research Data

Effect of diorganotin(IV) carboxylate complexes, [N‐(2‐carboxyphenyl) salicylideneiminato]dimethyltin(IV), bis(µ3‐oxo)bis(µ‐O‐aminobenzoato‐O,O′) bis(O‐aminobenzoato)tetrakis[dimethyltin(IV)] and bis(O‐aminobenzoato‐O,O′) di‐n‐butyltin(IV), on the membrane of Candida albicans cells—a mechanistic investigation of the antifungal activity of organotin complexes
Source: (:unav)
Antitumour activity of tin compounds
Source: Springer Netherlands
Antimicrobial activity of organotin(IV) compounds: a review
Source: Wiley
Synthesis, characterization and antibacterial activity of 3‐(2‐methoxyphenyl)‐2‐sulfanylpropenoic acid and di‐isopropylammonium [3‐(2‐methoxyphenyl)‐2‐sulfanylpropenoato] triphenylstannate(IV). The crystal structure of [HQ][SnPh3(o‐mpspa)]
Source: Wiley
Tin Compounds and their Potential as Pharmaceutical Agents
Source: Springer Berlin Heidelberg
Synthetic, Spectroscopic, Crystallographic, and Biological Studies of Seven-Coordinated Diorganotin(iv) Complexes Derived from Schiff Bases and Pyridinic Carboxylic Acids
Source: CSIRO Publishing

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