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Original Articles

Increased plasma free fatty acid and triglyceride levels after single administration of toluene in rabbits

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Pages 87-95 | Received 21 May 1987, Accepted 22 Feb 1988, Published online: 19 Oct 2009
 

Abstract

Changes of plasma lipids (triglyceride, TG: total cholesterol, Cho; and phospholipids, PL), free fatty acid (FFA), and blood glucose (BC) were studied in male rabbits after toluene administration (0.5 g/kg per os). Hypertriglyceridemia was observed at and after 2 h. Plasma FFA and BC were elevated temporarily during the early stage and lowered gradually thereafter. Initially, plasma Cho and PL were virtually unchanged, but the Cho level increased slowly after 6 h. The hypertriglyceridemia observed may have some adverse effects on heart function.

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