Urinary cadmium and beta₂‐microglobulin: Correlation with nutrition and smoking history

Norman E. Kowal Toxicology and Microbiology Division, Health Effects Research Laboratory, U.S. Environmental Protection Agency, 26 W. M. L. King Dr., Cincinnati, Ohio, 45268

Pages 179-183 | Received 24 Jul 1987, Accepted 09 Apr 1988, Published online: 20 Oct 2009

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https://doi.org/10.1080/15287398809531199

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Abstract

Urinary cadmium and beta₂‐microglobulin concentrations from approximately 1000 samples from the general adult U.S. population, collected as part of the National Health and Nutritional Examination Survey II (NHANES II), were related to nutritional and smoking history of the individuals. Urinary cadmium concentration was negatively correlated with dietary iron (significance level of 0.0065), negatively correlated with dietary calcium (significance level of <0.0001), and significantly (level of <0.001) higher in past or present smokers than in those who had never smoked. The results suggest increased cadmium absorption in the presence of low dietary intake of iron, low dietary intake of calcium, and cigarette smoking in the general population of the United States.

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