The effects of extremely low frequency electromagnetic fields exposure at 1 mT on hemogram and blood biochemisgtry in rats

ABSTRACT

The biological effects of extremely low-frequency electromagnetic fields (ELF-EMF) exposure are not fully clarified. We conducted this investigation to explore the effects of ELF-EMF on hematologic and biochemical indexes in adult rats. Thirty adult male Sprague–Dawley rats were exposed to ELF-EMF at 1 mT for 24 weeks, while another 30 SD rats were sham exposed. During the exposure, peripheral blood was collected every 4 weeks to analyze the hematologic parameters and biochemical indexes. The morphology of liver and kidney was detected by hematoxylin–eosin staining at the end of the experiment. Exposed to ELF-EMF at 1 mT did not exert any statistic difference on hematologic parameters including total white blood cell count, neutrophil ratio, lymphocyte ratio, red blood cells, hemoglobin concentration and platelets count, compared to the control group. Similarly, biochemical indexes, such as glucose, lipid profile, liver function and renal function, were not affected by ELF-EMF exposure. In addition, no morphological change was observed in the liver and kidney from the exposure group. The exposure to ELF-EMF at the intensity of 1 mT for 24 weeks did not affect hematologic and biochemical indexes in adult rats.

KEYWORDS:

• ELF-EMF
• hematologic parameters
• biochemical indexes
• adult rat

Author contributions

JW and SY conceived of and designed the experiments, performed the experiments, analysed the data, and contributed to the writing of the manuscript. XL and YZ conceived of and designed the experiments, performed the experiments, analysed the data, and contributed the analysis tools. LD, XW and MH and GR performed the animal experiments. JL and CC conceived of and designed the experiments and contributed to the writing of the manuscript. All authors read and approved the final manuscript.

Conflicts of interest

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was supported by the National Natural Science Foundation of China under Grants [51607163 to Y. Z. and 51707076 to J. L.] and The Science and Technology Project of the State Grid Corporation of China under Grant [GY71-16-008 to C.C.].