Associations Between a Dopamine D4 Receptor Gene, Alcohol Use, and Sexual Behaviors Among Female Adolescent African Americans

Jessica M. SalesRollins School of Public Health, Department of Behavioral Sciences and Health Education, Atlanta, Georgia, USA;Emory University Center for AIDS Research, Atlanta, Georgia, USA;Social & Behavioral Sciences Core, Athens, Georgia, USA;Center for Contextual Genetics and Prevention Science, University of Georgia, Athens, Georgia, USACorrespondence[email protected]

, PhD,

Erica L. SmearmanRollins School of Public Health, Department of Behavioral Sciences and Health Education, Atlanta, Georgia, USA;Emory University School of Medicine, Medical Scientist Training Program, Atlanta, Georgia, USA

, BS,

Jennifer L. BrownRollins School of Public Health, Department of Behavioral Sciences and Health Education, Atlanta, Georgia, USA;Emory University Center for AIDS Research, Social & Behavioral Sciences Core, Atlanta, Georgia, USA

, PhD,

Gene H. BrodyRollins School of Public Health, Department of Behavioral Sciences and Health Education, Atlanta, Georgia, USA;Emory University Center for AIDS Research, Atlanta, Georgia, USA;Social & Behavioral Sciences Core, Athens, Georgia, USA;Center for Contextual Genetics and Prevention Science, University of Georgia, Athens, Georgia, USA

, PhD,

Robert A. PhilibertCenter for Contextual Genetics and Prevention Science, University of Georgia, Athens, Georgia, USA;Department of Psychiatry, University of Iowa, Iowa City, Iowa, USA

, MD, PhD,

Eve RoseRollins School of Public Health, Department of Behavioral Sciences and Health Education, Atlanta, Georgia, USA

, MSPH &

Ralph J. DiClementeRollins School of Public Health, Department of Behavioral Sciences and Health Education, Atlanta, Georgia, USA;Emory University Center for AIDS Research, Atlanta, Georgia, USA;Social & Behavioral Sciences Core, Athens, Georgia, USA;Center for Contextual Genetics and Prevention Science, University of Georgia, Athens, Georgia, USA

, PhD show all

Abstract

Young female adolescent African Americans are disproportionately impacted by HIV infection. There is a clear need to understand factors associated with increased HIV-risk behaviors among this vulnerable population. We sought to explore the association between a dopamine D4 receptor gene (DRD4), a genetic marker associated with natural variations in rewarding behaviors, and self-reported alcohol use and sexual risk behaviors, while controlling for other known correlates of risk-taking such as impulsivity, sensation-seeking, and peer norms, among a group of high-risk female adolescent African Americans to evaluate whether this biological factor enhances understanding of the patterns of risk in this vulnerable group.

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Associations Between a Dopamine D4 Receptor Gene, Alcohol Use, and Sexual Behaviors Among Female Adolescent African Americans

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Associations Between a Dopamine D4 Receptor Gene, Alcohol Use, and Sexual Behaviors Among Female Adolescent African Americans

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